代表性教学、科研项目或研究成果(论文、专利专著、教材、成果获奖) |
科研项目: (1) 国家自然科学基金委员会, 地区科学基金项目, 82260696, 趋向淋巴转运的口服20α-羟基黄体酮甘油三脂前药的构建及转运机制研究, 2023-01-01 至 2026-12-31, 33万元, 在研,主持 (2) 新疆维吾尔自治区科学技术厅, 自然科学基金杰出青年项目, 2022D01E54, 基于特异性生物转化规律构建趋向淋巴转运的口服孕激素20α-羟基黄体酮甘油三酯前药系统, 2022-12-16 至 2025-12-15, 50万元, 在研,主持 (3) 国家自然科学基金委员会, 地区科学基金项目, 81960702, 基于调节树突状细胞抗原提呈功能的胀果甘草多糖抗肿瘤免疫作用及其分子机制研究, 2020-01-01 至 2023-12-31, 34万元, 在研, 参与 (4) 新疆维吾尔自治区科学技术厅, 自然科学基金青年项目, 2016D01C181, 哈药别克参多糖成分提取纯化、理化性质及免疫调节活性研究, 2017-01 至 2020-06, 5万元, 结题, 主持 科研论文: (1) Shujing Yan, Yuexuan Cheng, Liangyun Li, Chunhong Zhong, Chunli Chen*, Xiaoli Gao*. Lipid-based formulations: A promising approach for poorly soluble drug delivery via the intestinal lymphatic system[J]. Journal of Drug Delivery Science and Technology, 2023, 87: 104770. (2) Shanshan Gao, Shujing Yan, Yue Zhou, Yue Feng, Xiangyun Xie, Wei Guo, Qi Shen, Chunli Chen*. Optimisation of enzyme-assisted extraction of Erythronium sibiricum bulb polysaccharide and its effects on immunomodulation[J]. Glycoconjugate Journal, 2022, 39(3): 357-368 (3) Yue Zhou, Shujing Yan, Shanshan Gao, Wei Guo, Xiangyun Xie, Gulibahar Kawul, Mei Wang, Yue Feng, Chunli Chen*. Optimization of the composite enzyme extraction of polysaccharide from Erythronium sibiricum bulb and its immunoregulatory activities[J].Preparative Biochemistry & Biotechnology, 2021, 52(6): 681-690. (4) Chunli Chen, Xiangyun Xie, Xue Li. Immunomodulatory effects of four polysaccharides purified from Erythronium sibiricum bulb on macrophages[J]. Glycoconjugate Journal, 2021, 38: 517-525 (5) Chunli Chen, Rena Kasimu, Xiangyun Xie, Yanling Zheng, Wenhuan Ding. Optimised extraction of Erythronium sibiricum bulb polysaccharides and evaluation of their bioactivities[J]. International Journal of Biological Macromolecules, 2016, 82:898-904 (6) Rena Kasimu, Chunli Chen, Xiangyun Xie, Xue Li. Water-soluble polysaccharide from Erythronium sibiricum bulb:Structural characterisation and immunomodulating activity[J]. International Journal of Biological Macromolecules, 2017, 105:452-462 科研奖励: 2016年12月,撰写的论文Optimised extraction of Erythronium sibiricum bulb polysaccharides and evaluation of their bioactivities荣获第十四届新疆维吾尔自治区自然科学优秀学术论文三等奖,排名第一。 授权专利: 热娜·卡斯木; 陈春丽; 李新霞; 别克参多糖的制备方法及其应用, 2016-11-16, 中国, ZL 2014 1 0 382303.4 |